PRESENTATION OBJECTIVES

At the conclusion of this presentation, attendees will be able to:

1. Recognize that endogenous neuroprotectant pathways are activated in the acute, subacute and delayed periods after CNS injury

2. Recognize that some pathways contribute dichotomous detrimental and beneficial effects depending on the timing, cellular localization and other key facets of the injury

3. Obtain an in depth understanding of two representative pathways that exhibit dichotomous roles in CNS injury, namely adenosine and inducible nitric oxide synthase.