SPEAKER PRESENTATION OBJECTIVES

" Mitochondrial Dysfunction in Acute CNS Injury”

1. Define and discuss the neuropathological changes that occur following traumatic brain and spinal cord injury.
2. Understand and discuss the relationship between mitochondrial membrane potential, reactive oxygen species production, calcium uptake and membrane permeability.
3. Describe the mechanisms of action for mitochondrial uncouplers and mitochondrial membrane peremeabitliy inhibitors.
4. Indentify and discuss the pivotal role of mitochondria in traumatic brain and spinal cord injury.