WELCOME RECEPTION

*Included in registration for all attendees*

08:00 - 08:30

08:30 - 10:15

1.75 CME

WELCOMING REMARKS - David Hovda, Neil Martin & Donald Becker

L1: THE CHANGING FACE OF NEUROTRAUMA (EPIDEMIOLOGY & INJURY CLASSIFICATION) Sponsored by Univ. of Kentucky SCoBIRC

Chairs:  Neil Martin & Jacqueline Bresnahan

TRANSITIONING TO A NEW ERA: GLOBAL DEMOGRAPHICS OF TBI

Andrew Maas, Univ Hospital Antwerp 

GLOBAL DEMOGRAPHICS OF SCI

Charles Tator, Univ. of Toronto 

UPDATES ON THE CLASSIFICATION OF NEUROTRAUMA

Geoffrey Manley, UCSF 

YOUNGER IS NOT ALWAYS BETTER

David Adelson, Phoenix Children's Neuroscience Institute 

POSTER SESSION - GROUP A (Posters 1 - 131)

Supported by Solvay Pharmaceuticals

FINAL STUDENT COMPETITION JUDGING-ALL TOP POSTER FINALISTS

COFFEE BREAK - Sponsored by Casa Colina Center for Rehabilitation

VISIT EXHIBITS

11:45 - 01:00

1.25 CME

B1: INFLAMMATION & IMMUNITY

Chair:  Michael Beattie

THE INFLAMMATORY RESPONSE: NOVEL TARGETS IN ACUTE BRAIN INJURY

Maria Grazia de Simoni, Negri Institute

THE BRIGHT SIDE OF SYSTEMIC T CELLS AND BLOOD MONOCYTES AS WELL AS THE GLIAL SCAR FOR CNS REPAIR

Michal Schwartz, The Weizmann Inst. of Science

11:45 - 01:00

1.25 CME

B2: SPORTS-NEUROTRAUMA

Chair: Michael Collins

SPINAL NEUROTRAUMA IN SPORT

Allan Levi, UM School of Med

PEDIATRIC ISSUES IN SPORTS CONCUSSION ASSESSMENT AND MANAGEMENT

Gerard Gioia, Children's National Medical Center

SPORTS CONCUSSION:  SMOKE BUT NO FIRE?

James Kelly, Univ. of Colorado

11:45 - 01:00

1.25 CME

B3:  WHITE MATTER INJURY:  ARE WE MISSING THE FOREST FOR THE TREES?

Chair: Eva Sykova

OVERCOMING INHIBITORY PROTEOGLYCANS TO PROMOTE RECOVERY AFTER CNS DAMAGE

J.W Fawcett, Univ. of Cambridge 

IMAGING TRAUMATIC AXONAL INJURY

David Brody, Washington Univ. in St. Louis 

BRAIN DEVELOPMENT AND THE IMPACT OF TBI 

Elizabeth Sowell, UCLA 

01:00 - 02:30

1.5 CEU

SPECIAL NURSE LUNCHEON SEMINAR

THE ROLE OF THE NURSE PRACTITIONER IN A PEDIATRIC TBI CLINIC

Sue Yudovin, UCLA Medical Center

OPPORTUNITIES AND CHALLENGES IN TBI RESEARCH

Mary E. Kerr, National Institute of Nursing Research, NIH

WINTR BUSINESS MEETING

Open to all WiNTR members

INTS EXECUTIVE COMMITTEE MEETING

(members only)

02:30 - 04:10

1.75 CME

L2: THE GOLDEN HOUR: PREHOSPITAL MANAGEMENT OF NEUROTRAUMA AND POLYTRAUMA

Chairs:  Ji-Yao Jiang & Daniel Davis

A BRAVE NEW WORLD: COMBAT NEUROTRAUMA AND POLYTRAUMA

Alisa Gean, Univ. California San Francisco 

PREHOSPITAL EMERGENCY CARE IN THE DEVELOPING WORLD

Gourikoumar Prusty, Calcutta Med. Research Institute 

VASOPRESSIN FOR TBI: FROM BENCHTOP TO BEDSIDE

Kenneth Proctor, Univ. of Miami 

THE GOLDEN HOUR: PREHOSPITAL MANAGEMENT OF NEUROTRAUMA AND POLYTRAUMA

Daniel Davis, Univ. of California

04:45 - 06:00

1.25 CME

B4: CEREBRAL MICRODIALYSIS

Chair: Paul Vespa

CLINICAL UTILITY OF CEREBRAL MICRODIALYSIS IN THE NEURO-ICU

Peter Hutchinson, Univ. of Cambridge

POTENTIAL ROLE OF CEREBRAL MICRODIALYSIS IN EARLY DRUG DEVELOPMENT IN THE NEURO-ICU

Ross Bullock, Univ. of Miami

POTENTIAL OF CEREBRAL MICRODIALYSIS FOR BIOMARKER MONITORING IN THE NEURO-ICU

Lars Hillered, Uppsala Univ.

04:45 - 06:25

1.25 CME

B5:  SECONDARY INJURY/SPREADING DEPRESSION

Chair: Anthony Strong

FUNCTIONAL IMPACT OF CORTICAL SPREADING DEPRESSION

Otto Witte, Friedrich-Schiller Univ.

SPREADING DEPRESSION AND SECONDARY INJURY

Martin Fabricius, Univ. of Copenhagen

SPREADING DEPRESSION AND THE SPINAL CORD

Ali Gorji, Univ. of Munster

NF-kB AND p53 - THE YIN AND YANG IN THE TRAUMATIC PENUMBRA

Nikolas Plesnila, Royal College of Surgeons

04:45 - 06:00

1.25 CME

B6:  IMAGING MILD TBI

Chair: Thomas McAllister

FMRI AFTER MTBI

Jamie Pardini, Univ. of Pittsburgh 

MRS AFTER MTBI

Roberto Vagnozzi, Univ. of Rome Tor Vergata 

DTI AFTER MTBI

Elizabeth Wilde, Baylor College of Medicine 

06:00 - 07:30

1.5 CME

NNS OFFICERS & COUNCILORS MEETING

*by invitation only*

08:30 - 10:15

1.75 CME

L3:  CONTROVERSIES IN NEUROTRAUMA: A WORLD VIEW

Sponsored by Centre for NeuroSkills & BHR Pharma LLC

*INTERACTIVE SESSION*

Chair:  Thomas Glenn and Christopher Giza

CLINICAL MANAGEMENT OF ACUTE TBI- CONCUSSION TO COMA

Neil Martin, UCLA 

POSTER SESSION - GROUP B (Posters 132-262) Supported by Solvay Pharmaceuticals

COFFEE BREAK & VISIT EXHIBITS

11:45 - 01:00

1.25 CME

B7: HYPOTHERMIA

Chair: David Adelson

HYPOTHERMIA:  RISK AND CONCERNS IN PEDIATRICS

Jamie Hutchison, The Hospital for Sick Children 

CONTROLLED THERAPEUTIC HYPOTHERMIA - BENEFICIAL IF PROPERLY APPLIED

Kees Polderman, Utrecht Univ. Medical Center 

THERAPEUTIC HYPOTHERMIA AND SPINAL CORD INJURY

Dalton Dietrich, Univ. of Miami 

11:45 - 01:00

1.25 CME

B8: MANAGING EDEMA

Chair:  Jean Soustiel

PATHOPHYSIOLOGY AND SURGICAL STRATEGIES OF CEREBRAL CONTUSION 

Katsuji Shima, Nat'l. Defense Med. College 

SCI AND EDEMA CONTROL

Steven Casha, Foothills Hospital & Medical Centre 

DECOMPRESSIVE CRANIOTOMY FOR CHILDREN

Anthony Figaji, Univ. of Cape Town 

11:45 - 01:00

1.25 CME

OPEN COMMUNICATIONS SESSION A

Chair: Diane Snow

P1:IMPROVED CLINICAL CORRELATION OF CERVICAL SPINAL CORD MAGNETIC RESONANCE IMAGING WITH MOTOR AND SENSORY DEFICITS UTILIZING DIFFUSION TENSOR IMAGING AND TRACTOGRAPHY

Fahad Alkherayf, University of Ottawa

P109:A NOVEL APPROACH FOR THE TREATMENT OF SECONDARY EXCITOTOXICITY AFTER BRAIN TRAUMA BY CORRECTING DYSFUNCTIONAL AMPA RECEPTOR TRAFFICKING

Joshua Bell, University of Toronto

P301:A TRANSGENIC APPROACH TO THE STUDY OF THE CONSEQUENCES OF DIFFUSE AXONAL INJURY.

John Greer, Virginia Commonwealth University

P362:POLOXAMER P188 ATTENUATES CELL MEMBRANE PERMEABILITY, AND IMPROVES HISTOPATHOLOGICAL AND FUNCTIONAL OUTCOME FOLLOWING TRAUMATIC BRAIN INJURY IN MICE

Lamin Han Mbye, Harvard Medical School

P300:POSTINJURY MATRIX METALLOPROTEINASE INHIBITION TARGETING THE ONSET OF SYNAPTOGENESIS ENHANCES SYNAPTIC EFFICACY AND PROMOTES LONG-TERM SYNAPSE STABILIZATION

Kelly Warren, Viginia Commonwealth University

01:00 - 02:30

1.25 CME

WINTR SPECIAL LUNCHEON SEMINAR:

MERITS OF INTERNATIONAL COLLABORATION

Esther Shohami, Hebrew University

02:30 - 04:10

1.75 CME

L4: FORWARD TO THE FUTURE: NEW TECHNOLOGIES IN RESEARCH AND CLINICAL CARE (NEUROENGINEERING AND NANOTECHNOLOGY)

Chairs:  Michael Fehlings & Susan Margulies

ENGINEERING BETTER MODELS OF NEUROTRAUMA

King Yang, Wayne State Univ 

NEUROENGINEERING AND SC TRANSPLANTATION

Alexandros Lavdas, Hellenic Pasteur Institute 

COGNITIVE NEURAL PROSTHETICS: TOWARD RESTORING FUNCTION TO MOTOR-IMPAIRED INDIVIDUALS

Richard Anderson, California Inst. of Technology 

NEUROSURGICAL REHABILITAION: CONTROL OF MOVEMENT DISORDERS BY CHRONIC MOTOR CORTEX STIMULATION

Takeshi Maeda , Nihon Univ

04:45 - 06:00

1.25 CME

B9: CPP THERAPY

Chair:  Claudia Robertson

THE LUND CONCEPT:  EVIDENCE-BASED MEDICINE FOR NON-SURGICAL ICP REDUCTION

Carl-Henrik Nordstrom, Lund University Hospital 

CEREBRAL BLOOD FLOW MONITORING

Monica Vavilala, Univ. of Washington 

CEREBRAL PERFUSION PRESSURE IN CHILDREN: A COMPLEX "EXPOSURE" IN CHILDREN

Robert Tasker, Univ. of Cambridge 

04:45 - 06:00

1.25 CME

B10: MR IMAGING ADVANCES

Chair: Ramon Diaz-Arrastia

ADVANCED MR IMAGING TECHNIQUES IN PEDIATRIC TBI: SWI AND MULTIVOXEL MRSI

Karen Tong, Loma Linda Univ. 

DIFFUSION TENSOR IMAGING AND RELATIONSHIP TO OUTCOME AFTER TBI

Annette Sidaros, Copenhagen Univ. Hospital 

ADVANCES IN MR IMAGING TECHNIQUES TO MONITOR BRAIN CONNECTIVITY AND FUNCTION AFTER EXPERIMENTAL CNS TRAUMA

Neil Harris, UCLA 

 04:45 - 06:00

1.25 CME

B11: OBJECTIVE ASSESSMENT OF MILD TBI

Chair: Kenneth Curley

BIOMARKERS FOR MILD TBI

Kevin Wang, Banyan Biomarkers, Inc.. 

ASSESSMENT OF MILD TBI IN ANIMAL MODELS

Jonathan Lifshitz, University of Kentucky 

THE BRAIN ACOUSTIC MONITOR:  UPDATE ON CLINICAL EVALUATION OF USE FOR ASSESSMENT OF CLOSED HEAD INJURY IN CIVILIANS

Richard Dutton, Univ. of Maryland 

06:00 - 07:30

1.5 CME

WINE & CHEESE POSTER SESSION- GROUP B (Posters 132-262)

Supported by Solvay Pharmaceuticals

07:45 - 9:45

1.00 CME

WINTR MENTORING PROGRAM & NETWORKING RECEPTION

*Optional Ticketed Event - purchase tickets with your registration*

08:30 - 10:15

1.75 CME

L5: SAVING NEURONS AND GROWING NEURONS (NEUROPROTECTION AND NEUROGENESIS)

Chair:  Michael Chopp & Pak Chan

NEUROPROTECTION AND VULNERABILITY IN THE IMMATURE BRAIN

Chrysanthy Ikonomidou, Technical Univ. Dresden

STEM CELLS NEUROGENESIS AND ACQUIRED BRAIN INJURY

Steven Kernie, UT Southwestern Medical Center 

NEUROPHYSIOLOGICAL MECHANISMS OF RECOVERY OF LOCOMOTION AFTER SPINAL INJURY

Reggie Edgerton, UCLA 

IN VIVO TRACKING OF STEM CELLS IN TBI AND SCI

Eva Sykova, EU Centre of Excellence 

POSTER SESSION - GROUP C (Posters 263-392) Sponsored by Solvay Pharmaceuticals

COFFEE BREAK & VISIT EXHIBITS

11:45 - 01:00

1.25 CME

B12: NUTRITION AND RECOVERY

Chair:  Carol Braunshweig

DIET AND EXERCISE THERAPY FOR TBI

Sandeep Sharma, University of California 

NUTRIENT HOMEOSTASIS AND FUNCTIONAL OUTCOME AFTER TBI

Christophe Moinard, Univ. Paris Descartes 

Carol Braunschweig, University of Illinois

11:45 - 01:00

1.25 CME

B13: AUTONOMIC DYSFUNCTION

Chair: Arthur Brown

GASTROINTESTINAL DYSFUNCTION AFTER SCI

Gregory Holmes, Pennington Biomed Research Center 

METABOLIC AND AUTONOMIC CONSEQUENCES OF SPINAL CORD INJURY

Ann Spungen, Mount Sinai School of Medicine NY 

Ian Baguley, University of Sydney 

11:45 - 01:00

1.25 CME

OPEN COMMUNICATIONS SESSION B

Chair:  Jean Wrathall

P116:DELAYED INSULIN-LIKE GROWTH FACTOR -1 OVEREXPRESSION PROVIDES REGIONAL NEUROPROTECTION DEPENDENT ON INJURY SEVERITY

Sindhu Kizhakke Madathil, University of Kentucky

P54:CERVICAL SPINAL CORD INJURY: A RELATIONSHIP BETWEEN COLUMN AND CORD STRAINS IN TENSION-EXTENSION INJURIES

Shannon Kroeker, University of Washington

P18:MASSIVE FLUX OF THE GLIOTRANSMITTER ATP INTO THE EXTRACELLULAR SPACE FOLLOWING TRAUMATIC BRAIN INJURY IN THE RAT.

Nobuhrio Moro, UCLA

P104:ANGIOPOIETIN-1 REDUCES BLOOD-SPINAL CORD BARRIER PERMEABILITY AND LESION VOLUME IN THE ACUTE PHASE OF SPINAL CORD INJURY: MRI AND HISTOLOGICAL STUDIES

Chirag Patel, University of Texas Medical School

P41:MCP-1 KNOCKOUT MICE EXHIBIT IMPROVED NEUROLOGICAL OUTCOME, ALTERED CYTOKINE PRODUCTION, REDUCED MACROPHAGE INFILTRATION AND REDUCED LESION VOLUME FOLLOWING FOCAL TRAUMATIC BRAIN INJURY

Bridgette Semple, National Trauma Research Institute

02:30 - 04:30

2.0 CME

02:30 - 03:00

03:00 - 03:30

03:30 - 04:00

04:00 - 04:30

BLAST TBI: UPDATES FROM THE US DOD CONSORTIUMS

PREVENT - NEW INSIGHT INTO UNDERSTANDING AND TREATING BLAST TBI

Richard Bauman, PREVENT

TBA

Claudia Robertson

BLAST TBI; UPDATE FROM THE US DoD CONSURTIUMS

Col. Michael Jaffe, DVBIC

UPDATE CONSEQUENCES OF OPERATION IRAQUI FREEDOM AND OPERATION AFGHANI FREEDOM

Larry Marshall, UC San Diego Medical Center

02:30 - 05:30

3.0 CME

HANDS ON SPINAL WORKSHOP   *INTERACTIVE*

Sponsored by Codman, Synthes CMF, Integra Neuroscience

Chairs: Roland Torres & Stephen Casha

GALA DINNER & DANCE

*included in registration for all attendees*

08:30 - 10:15

1.75 CME

L6: METABOLISM AFTER NEUROTRAUMA: A GLOBAL ENERGY CRISIS? (METABOLISM)

Chair: John Pickard & Takeshi Maeda

WHAT'S IN A THINK TANK? THE QUEST FOR ALTERNATIVE FUELS

Thomas Glenn, UCLA 

POSTER SESSION - GROUP C (Posters 263-392) Supported by Solvay Pharmaceuticals

COFFEE BREAK & VISIT EXHIBITS

11:45 - 01:00

1.25 CME

B14: GLYCEMIC CONTROL

Chair: Diane Snow

CEREBRAL EFFECTS OF GLYCEMIC CONTROL IN PATIENTS WITH ANEURYSMAL SAH

Asita Sarrafzadeh, Charite Campus Virchow Medical Center 

Paul Vespa, UCLA 

Xavier Leverve, University Hospital Gasthuisberg 

 11:45 - 01:00

1.25 CME

B15:  EFFICACY OF REHABILITATION

Chair: Vicki Anderson

11:45 - 12:10 

EMERGING RESEARCH IN REHABILITATION FOR TRAUMATIC BRAIN INJURY

John Corrigan, Ohio State Univ. 

A RANDOMIZED CONTROLLED TRIAL OF MULTI-SENSORY ENVIRONMENTAL THERAPY AFTER PEDIATRIC NEUROTRAUMA

Gillian Hotz, Univ. of Miami 

A RANDOMIZED CONTROLLED TRIAL OF COGNITIVE REHAB AFTER TBI

Ingrid van't Hooft, Karolinska Institutet 

11:45 - 01:00

1.25 CME

OPEN COMMUNICATIONS SESSION C

Chair:  Chrysanthy Ikonomidou

P237:COGNITIVE AND SENSORIMOTOR RECOVERY AFTER FLUID-PERCUSSION BRAIN INJURY MODIFIED BY EARLY INTERMITTENT STIMULATION FOR ONE WEEK IN THE RAT’S DORSAL OR MEDIAN RAPHE.

Melissa Carballosa-Gonzalez, The Miami Project to Cure Paralysis

P145:BCL-2 GENOTYPES AND FUNCTIONAL AND COGNITIVE-BEHAVIORAL OUTCOMES AFTER SEVERE TRAUMATIC BRAIN INJURY

Nicole Hoh, University of Pittsburgh

P20:ENDOGENOUS SVZ NEURAL STEM AND PROGENITOR CELLS ARE STIMULATED TO DIVIDE AND GENERATE NEW CORTICAL CELLS FOLLOWING TRAUMATIC BRAIN INJURY.

Gretchen Miller, UCLA

P163:ESTROGEN PROTECTS SCHWANN CELLS AGAINST H2O2 INDUCED CYTOTOXICITY AND INCREASES TRANSPLANTED SCHWANN CELL SURVIVAL IN A CERVICAL HEMICONTUSION SPINAL CORD INJURY

Akkradate Sirphorn, University of Alabama at Birmingham

P117:CREATING GROWTH SUPPORTIVE PATHWAYS TO ENHANCE DOPAMINERGIC AXON GROWTH

Chen Zhang, University of Kentucky

NATIONAL NEUROTRAUMA SOCIETY BUSINESS MEETING

Open to all NNS members

02:30 - 04:10

1.75 CME

L7: REBUILDING AND REPAIRING THE INJURED NERVOUS SYSTEM (RECOVERY OF FUNCTION)

Chair:  Claire Hulsebosch and Esther Shohami

CORTICAL PLASTICITY AND RECOVERY FOLLOWING TBI

Dorothy Kozlowski, DePaul University 

EXPERIENCE-DEPENDENT PLASTICITY FOLLOWING DEVELOPMENTAL TBI

Christopher Giza, UCLA 

ASSESSING NEURAL REPAIR AND RECOVERY AFTER SPINAL CORD INJURY

Jacqueline Bresnahan, Univ. of California 

Henriette van Praag, National Institute on Aging (NIA)

04:30 - 05:45

1.25 CME

B16: SPINAL CORD-BRAIN INTERACTIONS

Chair: Reggie Edgerton

REORGANIZATION OF AN ASCENDING SENSORY TRACT'S BRAIN PROJECTIONS AFTER A PARTIAL SPINAL CORD INJURY

Stephen Onifer, University of Kentucky

GLIOPATHY CONTRIBUTES TO PERSISTENT INFLAMMATION AND DYSFUNCTION AFTER CNS TRAUMA

Claire Hulsebosch, University of Texas

INTERACTION OF PERIPHERAL INPUT AND DESCENDING MOTOR INPUT IN CONTROLLING LOCOMOTION

Yury Gerasimenko, Russian Academy of Sciences 

04:30 - 05:45

1.25 CME

B17:  CAPITALIZE ON NEUROPLASTICITY:  ACTIVATION OF INJURED NERVOUS SYSTEM

Chair: Dorothy Kozlowski

GLUTAMATE AGONIST THERAPY RESTORES FUNCTIONS IN EXPERIMENTAL TBI

Esther Shohami, The Hebrew Univ. 

EXERCISE AND RECOVERY AFTER TBI

Grace Griesbach, UCLA 

ACTIVATION OF PLASTICITY MECHANISMS FOLLOWING INJURY IN THE DEVELOPING AND MATURE NERVOUS SYSTEM

Paul Reier, UF & McKnight Brain Institute 

04:30 - 05:45

1.25 CME

B18:  TROPHIC FACTORS AND RECOVERY

Chair: Linda J. Noble

GROWTH FACTOR THERAPY:  LESSONS FROM IGF-I

Ignacio Torres-Aleman, Cajal Institute 

TROPHIC FACTORS AND MOOD DISORDERS

Marco Riva, Univ. of Milan 

NEW INSIGHTS INTO POST-TRAUMATIC EPILEPTOGENEIS

Ivan Soltesz, Univ. California Irvine 

06:00 - 06:15

L8: PATIENT PERSPECTIVE

Patrick Donohue, Sarah Jane Foundation

CLOSING SESSION & STUDENT AWARDS CEREMONY

INTS Scientific Advisory Board Meeting (by invitation only)