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Description & Objectives S19


Latest Advances in Functional Imaging After TBI Cross-Cutting


Dr. Edlow will discuss the use of fMRI and EEG in acute severe TBI for the identification of cortical processing and prediction of 6-month functional outcomes.

Dr. Wilde and Dr. Mac Donald will present on the relationship between structural MRI findings (volumetric and diffusion imaging) and cognitive, behavioral, and psychological outcome in active service members and veterans with TBI. Dr. Mac Donald will present longitudinal data spanning from acute/sub-acute presentation to 1 and 5 year post-injury, while Dr. Wilde will focus mostly on longer-term findings within the military population.

Dr. Coughlin will present insights gained from using positron emission tomography (PET) imaging to track the neuroimmune response after sports-related, repeated TBI, and to assess the relationship between neuroinflammation and onset of post-TBI cognitive or psychiatric symptoms in some individuals.


At the conclusion of this session, attendees will be able to:

  1. Describe how fMRI and EEG have been used to detect cortical processing in patients with acute severe TBI and no behavioral evidence of language expression and comprehension.

  2. Describe how advanced structural MRI may elucidate the integrity of structures and networks underlying various aspects of functioning in military personnel with mild TBI.

  3. Describe the relationship between inflammation markers from PET and psychiatric and cognitive outcome.